Scientists at the Barshop Institute have demonstrated that orally administered eRapa can
prevent the development of Alzheimer’s pathologies in mice.
Utilizing mice genetically prone to develop Alzheimer’s disease, UTHSCSA scientists have shown orally administered eRapa™ is effective in preventing the cognitive deficits of memory loss and anxiety, along with preventing the accumulation of amyloid-beta and tau proteins in brain which are both used as indicative, pathologic cerebral biomarkers for Alzheimer’s disease. UTHSCSA scientists have also shown eRapa administration increases intra-cerebral blood flow in brain regions of mice compromised by Alzheimer’s-related pathologies. We believe demonstration of eRapa-induced restoration of cerebral blood flow in our future clinical studies will lead to significant interest from potential commercial partners.
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